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A substance preventing the recurrence of or modifies certain periodic febrile diseases; or which counteracts periodic tendencies of any disease.

Culbreth, D.M.R. A Manual of Materia Medica and Pharmacology. Reprinted by Eclectic Med Publications: Portland, OR, 1983.

Elingwood, F. American Materia Medica, Therapeutics and Pharmacognosy. Eclectic Med Publications, Portland, OR, l983.