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Page 7 of 8 References supporting CellRenew and its components
1. Alkayali, A. Biocell Technology, LLC. "Hydrolyzed collagen type II
and use thereof," US Patent # 6,025, 327. February 15, 2000.
2. Knauper et al. "Biochemical characterization of human collagenase-3," J. Biol. Chem. 271:1544-1550 (1996).
3. Bedi et al. "Purification and characterization of a
collagen-degrading protease from Porphyromonas ginivalis," J. Biol.
Chem. 269:599-606 (1994).
4. Alkayali, A. Biocell
Technology, LLC. "Method of making hydrolyzed collagen type II," US
Patent # 6,323,319. February 15, 2000.
5. M. Barinaga, "Treating Arthritis With Tolerance," Science 261:1669-1670 (1993).
6. M.A. Cremer, et al., "Collagen-Induced Arthritis In Rats:
Antigen-Specific Suppression of Arthritis and Immunity By Intravenously
Injected Native Type II Collagen," The Journal of Immun. 131(6):
2995-3000 (1983).
7. M.E. Englert, et al., "Suppression of
Type II Collagen-Induced Arthritis by the Intravenous Administration of
Type II Collagen or Its Constituent Peptide .alpha..sub.1 (II)
CB.sub.10, " Cellular Immunology 87:357-365 (1984).
8. L.
Stryer, "Collagen Has An Unusual Amino Acid Composition And Sequence,"
Biochemistry, Third Edition, W.H. Freeman and Co., New York, p. 262
(1988).
9. D.E. Trentham, et al., "Autoimmunity to Type II
Collagen: An Experimental Model of Arthritis," The Journal of
Experimental Medicine 146:857-868 (1977).
10. D.E.
Trentham, et al., "Effects of Oral Administration of Type II Collagen
on Rheumatoid Arthritis," Science 261:1727-1730 (1993).
11. Brucknet et al. `p-HMW-Collagen, a minor collgen obtained form
chick embryo cartilage without proteolytic treatment of the tissue`,
Eur. J. Biochem. 136 : 333-339 (1983).
12. Trentham et al.
`Autoimmunity of Type II Collagen: An Experimental Model of Arthritis`,
J. of Exp. Medicine. 146 : 857-868 (1977).
13. Barnett,
ML, et al., "Treatment of rheumatoid arthritis with oral type II
collagen. Results of a multicenter, double-blind, placebo controlled
trial," Arthritis Rheum 41 (2) : 290-297 (1998).
14. Ronca
F, et al., "Anti-inflammatory activity of chondroitin sulfate,"
Osteoarthritis Cartilage suppl. 6 (A) : 14-21 (1998).
15. Moskowitz RW. "Hyaluronic acid supplementation," Curr Rheumatol Rep 2(6):466-71 (2000).
16. Anderson I. "The properties of hyaluronan and its role in wound healing," Prof Nurse 17(4):232-5 (2001).
17. Greco RM, et al., "Hyaluronic acid stimulates human fibroblast
proliferation within a collagen matrix," J Cell Physiol 177(3):465-73
(1998).
18. Ghersetich I., et al, "Hyaluronic acid in cutaneous intrinsic aging," Int J Dermatology 33 (2): 119-122 (1994).
19. Moskowitz RW. "Role of collagen hydrolysate in bone and joint disease," Semin Arthritis Rheum 30(2):87- 99,(2000)
20. Glaza, SM, "Acute oral toxicity study of BioCell collagen II™ in rats," Covance Laboratories. November 16, 2001.
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