Fatigue may be a complex clinical syndrome of uncertain etiology.
The diagnostic terminology may also vary: chronic fatigue syndrome, chronic fatigue immune dysfunction syndrome (CFIDS), epidemic myalgia, myalgic encephalomyelitis (ME/EM), chronic viral syndrome and post-viral fatigue syndrome.
It is characterized by incapacitating fatigue: "TATT" (tired all the time); although the concert of accompanying symtpoms can mimic, or actually represent, a host of other conditions. The "Top Ten" may be itemized as follows:-
A laboratory assay may help to differentiate this condition from other fatigue producing diseases e.g. AIDS, cancer and bacterial infections.
Muscle fatigue (pain/tenderness/myalgia); low grade fever; memory loss; moodiness; sleep disorders; neuropathology; tachycardia; cold extremities; sweating; palor and sluggish pupils.
As can be expected from such a diverse range of symtpoms, there is probably not one single cause of this syndrome but viral infections and environmental exposures are prime candidates.
The variety of viruses implicated in the development of CFIDS includes: Coxsackie, Cytomegalovirus (CMV), Epstein Barr (EBV), Herpes Simplex (HHV) and Polio.
Exposures have included pesticides and organic solvents.
Fatigue is a state of decreased efficiency and increased discomfort due to prolonged or excessive physical or emotional exertion.
There are several states of fatigue: Acute, chronic, and muscular.
Acute fatigue has a sudden onset such as occurs following excessive exercise. It is cured by rest.
Chronic fatigue continues for a long period of time. It is not relieved by rest and is indicative of an underlying disorder which alters body metabolism.
It has recently been linked with myalgic encephalomyelitis (ME).
Muscular fatigue, one of the most common forms of fatigue, is the reduced capacity of a muscle to perform work. This is caused by repeated muscular contractions.
Buchwald and Garrity recently compared patients with chronic fatigue syndrome, fibromyalgia and multiple chemical sensitivities, finding a common denominator in their mitochondrial oxidative phosphorylation disorders and oxidative stress, which produces lactate accumulation.
Bland proposes a number of nutritional modulators to bring about resuscitation of the mitochondria.
Any differential diagnosis must sort out the following factors:
Accumulation of metabolic waste products in the body for any reason;
Circulatory disturbances which deal with delivery of oxygen and energy materials, such as: Anemia and Heart disorders;
Respiratory disturbances which diminish the supply of oxygen to tissues such as: Tuberculosis;
Infections in which toxic products are produced or body metabolism is altered;
Endocrine disturbances such as:
Physical factors such as: excessive activity, disabilities or handicaps
Psychological factors such as:
Environmental noises and vibrations
Signs & Symptoms
Fatigue is itself a symptom of another state. Identifying factors of fatigue are:
Structure & Function:
Immune System Support
Support for Glucose Metabolism &
Adult Child/Adolescent B-Complex hi-potency hi-potency Brewer's yeast* Calcium 400 - 600 mg 200 - 300 mg Ginkgo Biloba* Magnesium 400 - 600 mg 200 - 300 mg Niacin 100 - 500 mg 50 - 300 mg Thiamine 50 - 100 mg 10 - 20 mg Tyrosine 500 - 1,000 mg 200 - 800 mg
* Please refer to the respective topic for specific nutrient amounts.
Note: All amounts are in addition to those supplements having a Recommended Dietary Allowance (RDA). Due to individual needs, one must always be aware of a possible undetermined effect when taking nutritional supplements. If any disturbances from the use of a particular supplement should occur, stop its use immediately and seek the care of a qualified health care professional.
Fatigue may be caused by the following deficiencies: folacin, pantothenic acid and vitamin B-12. Fatigue can also result from excess intake of dietary supplements. Chronic manganese toxicity produces muscle fatigue at dosage levels of one gram per day. Intake of 25,000 to 1,000,000 IU of vitamin A per day gives rise to fatigue in both adults and children. A high fat intake may be responsible for feelings of fatigue and nausea. Adherence to a Dietary Goals Diet corrects these symptoms.
If fatigue is caused by cerebral allergy, an Elimination Diet is recommended.
1. Gelsemium sempervirens - 30C 2. Ambra grisea - 30C 3.*Avena sativa tinct. - 30C 4.*Alfalfa tinct. - 30C
Advanced , by symptom:
1. Over-exertion - Arnica montana tinct.. 2. After mental effort, worry - Kali phosphoricum. 3. Anxiety, restlessness - Arsenicum Album. 4. Workaholic, intolerant - Nux vomica. 5. Fatigued and anxious - Calcarea carbonica
Doses cited are to be administered on a 3X daily schedule, unless otherwise indicated. Dose usually continued for 2 weeks. Liquid preparations usually use 8-10 drops per dose. Solid preps are usually 3 pellets per dose. Children use 1/2 dose.
X = 1 to 10 dilution - weak (triturition)
C = 1 to 100 dilution - weak (potency)
M = 1 to 1 million dilution (very strong)
X or C underlined means it is most useful potency
Asterisk (*) = Primary remedy. Means most necessary remedy. There may be more than one remedy - if so, use all of them.
Boericke, D.E., 1988. Homeopathic Materia Medica.
Coulter, C.R., 1986. Portraits of Homeopathic Medicines.
Kent, J.T., 1989. Repertory of the Homeopathic Materia Medica.
Koehler, G., 1989. Handbook of Homeopathy.
Shingale, J.N., 1992. Bedside Prescriber.
Smith, Trevor, 1989. Homeopathic Medicine.
Ullman, Dana, 1991. The One Minute (or so) Healer.
Note: The misdirected use of an herb can produce severely adverse effects, especially in combination with prescription drugs. This Herbal information is for educational purposes and is not intended as a replacement for medical advice.
Aromatherapy - Essential Oils
Basil Essence, Bergamot Essence, Cassia Essence, Chamomile Essence, Clary Sage Essence, Clove Essence, Frankincense Essence, Lavender Essence, Lemon Essence, Neroli Essence, Orange Essence, Petitgrain Essence, Rosemary Essence, Sage Essence, Thyme Essence.
Related Health ConditionsAbstracts
Adams, E.J. & L.K. Mahan. 1984. Nutritional care in food allergy and food intolerance. Food, Nutrition, and Diet Therapy. M.V. Krause and L.K. Mahan eds.
Behan, P.O. et al: Effect of High Doses of Essential Fatty Acids on The Postviral Fatigue Syndrome. ACTA Neurol. Scand., 1990; 82:209-216.
Bland, Jeffrey. Medical Applications of Clinical Nutrition. New Canaan, Conn.: Keats, 1983.
Bland, Jeffrey. Nutraerobics. San Francisco: Harper & Row, 1983.
Bland, Jeffrey: New Perspectives in Nutritional Therapies: Improving Patient Outcomes. 1996. Health Comm.
Bolster-MB & Silver-RM: Eosinophilia-myalgia syndrome, toxic-oil syndrome, and diffuse fasciitis with eosinophilia. Curr-Opin-Rheumatol; 1994 Nov; 6(6); P 642-9.
Buchwald, D. & Garrity, D. : Comparison of patients with chronic fatigue syndrome, fibromyalgia and multiple chemical sensitivities. Arch. Int. Med. 1994, 154: 2049 - 2053.
Clark, : Eating For Energy. The Physician and Sports Medicine, April 1991;19(4):45-48.
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Driskell-WJ et al: Identification of decomposition products of 1,1'-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome Bull.-Environ.-Contam.-Toxicol. vol. 48, no. 5, pp. 679-687, 1992.
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Valesini-G et al: chronic fatigue syndrome: what factors trigger it off? [editorial] Clin-Exp-Rheumatol; 1994 Sep-Oct; 12(5); P 473-6.
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