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Abstracts

Abstracts

Cancer & Astaxanthin

Cancer and Astaxanthin

The carotenoid astaxanthin may help to combat tumors by stimulating the immune response, according to this study conducted on mice. Researchers gave mice astaxanthin mixed in a chemically defined diet and then innoculated the mice with tumor cells. Tumor size and weight were determined three days after innoculation. Mice fed with astaxanthin exhibited significantly lower tumor size and weight if supplementation had begun 1-3 weeks before tumor innoculation. Supplemented mice also exhibited higher activity levels of cytotoxic T lymphocytes and interferon-gamma production by tumor-draining lymph node. These results indicate that astaxanthin suppresses tumor growth by stimulating an immune response against cancer cells.

Jyonouchi H, Sun S, Iijima K, Gross MD: Antitumor activity of astaxanthin and its mode of action, Nutr Cancer 2000;36(1):59-65