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Generic and Trade Names:



This drug mimics the effects of prostaglandin E1. It inhibits gastric acid secretion and protects the gastric mucosa by increasing mucous and bicarbonate production. It is used primarily to protect the gastric mucosa from the side effects associated with NSAID use. (Facts and Comparisons 1999)

Nutritional Considerations:

Take with food. (Pronsky 1999)

Supplementation with antacids, containing magnesium may increase diarrhea. (Pronsky 1999)

Avoid or limit alcohol. (Facts and Comparisons 1999)

Herbal Considerations:

None known at this time


Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 1999.

Pronsky, Zaneta M. Food Medication Interactions, 11th edition, 1999.


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