Skeletal Muscle Relaxants
Written by Med-Scope
Skeletal Muscle Relaxants
Generic and Trade Names:
Baclofen Lioresal Carisoprodol Soma Chlorphenesin carbamate Maolate Chlorzoxazone Parafon Forte, Paraflex Cyclobenzaprine Flexeril Dantrolene sodium Dantrium Diazepam Valium Metaxolone Skelaxin Methocarbamol Robaxin Orphenadine citrate Norflex Tizanidine Zanaflex
Description:
These agents work in various ways to manage skeletal muscle pain or spasms. They range from working directly at the site of spasms to a general central nervous system depression to relieve pain and relax skeletal muscles. (Facts and Comparisons 1999)
Nutritional Considerations:
Grapefruit juice may interact with diazepam by increasing its duration of effect. (Ozdemir 1998)
Avoid alcohol. (Facts and Comparisons 1999)
Avoid caffeine: in coffee, black and green tea. (Brinker 1998)
Herbal Considerations:
The caffeine in cocoa, cola, guarana, mate, may interact with diazepam to decrease its sedative effects. (Brinker 1998)
Depolarizing muscle relaxants may theoretically interact with cardioactive herbs to increase the risk of arrhythmias. (Newall 1996)
Herb
Broom Alkaloids,
Calamus
Cereus Tyramine,
Cola Caffeine
Coltsfoot
Devil's Claw
Fenugreek
Figwort
Fumitory
Ginger
References
Brinker, Francis N.D. Herb Contraindications and Drug Interactions. Eclectic Medical Publications, 1998.
Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 1999.
Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
Ozdemir M, Aktan Y, Boydag BS. Interaction between grapefruit juice and diazepam in humans. Eur J Drug Metab Pharmacokinet 1998; 23:55-9.
Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999.
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