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Migraine Medications

Migraine Medications

Dihydroergotamine mesylate (D.H.E. 45)
Ergotamine (Ergostat)
Rizatriptan (Maxalt)
Sumatriptan (Imitrex)
Zolmitriptan (Zomig)

Nutritional Considerations:

Avoid caffeine. (McKevoy 1998)

Limit smoking. (AMA, 1998)

Limit alcohol use, which can aggravate drug side effects. (Scott 1994)

Herbal Considerations:

Avoid St. John's Wort. (Franklin 1999) (Pronsky 1999)

Black tea, cola nut, guarana, green tea, and mate can all increase the GI absorption of ergotamine. (McKevoy 1998)

The herb Ginkgo Biloba may affect the central nervous system and should not be used in combination with the above drugs. (Newall 1996)


AMA. http://www.ama-assn.org/insight/spec_con/migraine/modmig.htm

Franklin M, Chi J, McGavin C Hockney R, Reed A, Campling G Whale RW, Cowen PJ. Neuroendocrine evidence of dopaminergic actions of hypericum extract (LI 160). Biol Psychiatry. 1999 Aug 15;46(4): 581-4

McKevoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.

Pronsky, Z Food Medication Interactions, 11th edition 1999

Scott AK: Sumatriptan clinical pharmacokinetics. Clin Pharmacokinet, 1994 Nov, 27:5, 337-44.