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Prostate Medications

Prostate Medications

Finasteride (Proscar, Propecia)

Nutritional Considerations:

Avoid caffeine, alcohol and spicy foods. (Germano 1995)

Zinc, selenium, and the amino acids (glutamic acid, alanine and glycine) may be beneficial. Ask your pharmacist regarding necessary supplementation. (Dumrau 1962) (Schrodt 1964) (Webber 1985)

Herbal Considerations:

African pygeum and saw palmetto have hormonal activity and may have additive effects on proscar. Consult your pharmacist concerning the safety of taking these herbs with the drug. (Bassi 1987)(Carilla 1984)

Herbs with steroid components e.g. Sarsaparilla may increase side effects of finasteride and must not be taken together. (Newall 1996)

Avoid cernilton (an herbal product made from rye grass pollen) with Propecia, (same as Proscar) , without consulting a pharmacist. There may be additive effects. (Habid 1990) (Horii 1985) (Suzuki 1992)

References

Bassi, P., et al, "Standardized Extract of Pygeum africanum in the Treatment of Benign Prostatic Hypertrophy", Minerva Urologica 39:45, 1987

Carilla, E., et al, "Binding of Permixon (Saw Palmetto Extract), A New Treatment For Prostatic Benign Hyperplsia", J Steroid Biochem 20 (1): 521-523, 1984

Dumrau, F., "Benign Prostatic Hyperplasia: Amino Acid Therapy for Symptomatic Relief", Am J Geriatrics 10:426-30, 1962

Germano, Carl M.A.,R.D.,CNS, "Nutritional Considerations in Benign Prostate Enlargement" 1995

Habib FK, Ross M, Buck AC, et al. In vitro evaluation of the pollen extract, cernitin T-60, in the regulation of prostate cell growth. Br J Urol 1990;66:393-97.

Horii A, Iwai S, Maekawa M, Tsujita M. Clinical evaluation of Cernilton in the treatment of the benign prostatic hypertrophy. Hinyokika Kiyo 1985;31:739-45 (in Japanese).

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996

Schrodt, GR, et al, "The Concentration of Zinc in Diseased Human Prostate Glands", Cancer 17:1555-66, 1964

Suzuki T, Kurokawa K, Mashimo T, et al. Clinical effect of Cernilton in chronic prostatitis. Hinyokika Kiyo 1992;38:489-94 [in Japanese].

Webber, MM, "Selenium Prevents the Growth Stimulatory Effects of Cadmium on Human Prostatic Epithelium", Biochem Biophy res Commun 127(3):871-77, 1985