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Lobeline is an alkaloid found in lobelia and other plants. Lobeline has many pharmacological activities, such as to act as a central nervous system stimulant and, subsequently, a depressant. Lobeline is also an expectorant. In large amounts it causes vomiting and acts as a diuretic. In excessive amounts, it will lead to convulsions and collapse, and can lead to death. Therapeutically, lobeline is used as a respiratory stimulant.

Leung, Albert Y. 1980. Encyclopedia of Common Natural Ingredient used in Food, Drugs and Cosmetics. John Wiley and Sons, N Y. 409 pp.

Windholz, Martha, Susan Budavani, et. al. 1976. The Merck Index. Merck and Co., Inc. New Jersey.