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Podophyllotoxin is a lignan found in podophyllum and other plants (see under May apple).

Podophyllotoxin has shown growth-retarding and embryocidal properties on experimental animals. It also has been shown to have antitumor properties and is used therapeutically as an antineoplastic agent.

Leung, Albert Y. 1980. Encyclopedia of Common Natural Ingredient used in Food, Drugs and Cosmetics. John Wiley and Sons, N Y. 409 pp.

Windholz, Martha, Susan Budavani, et. al. 1976. The Merck Index. Merck and Co., Inc. New Jersey.