Bromelain is a proteolytic and milk-clotting enzyme protease obtained from the juice of the pineapple plant. Bromelain is used as adjunctive therapy to reduce inflammation and edema, and to accelerate tissue repair, especially following episiotomy.
The German Commission E recommends a limited duration for the use of this herb of 8 - 10 days.
Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
Facts and Comparisons. The Lawrence Review of Natural Products. Jan, 1998.
Lotz-Winter, H: On the pharmacology of bromelain: an update with special regard to animal studies on dose-dependent effects. Planta med. 1990, 56:249.
Peaston, M.J.T. & P. Finnegan. 1968. A case of combined poisoning with chlorpropamide, acetylsalicylic acid and paracetamol. British Journal of Clinical Practice, 22.
Rowan, AD et al., The cysteine proteinases of the pineapple plant. Biochem J. 1990a, 266(3):869.
Rowan, AD et al., Debridement of experimental full-thickness skin burns of rats with enzyme fractions derived from pineapple stem. Burns, 1990b, 16(4):243.
Tyler, Varro E., Lynn R. Brady, et. al. 1981. Pharmacognosy. Lea and Febiger, Philadelphia. 520.
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