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Cortisone is a hormone isolated from the cortex of the adrenal gland and also prepared synthetically. It is believed to be both a precursor and metabolite of cortisol (hydrocortisone). Prior to this conversion to cortisol it is largely inactive.

Cortisone is important for its regulatory action in the metabolism of proteins, carbohydrates, fats, sodium, and potassium. Pharmacologically as an anti-inflammatory in various conditions, including allergies, collagen diseases and adrenocortisol replacement therapy. Disadvantages may include temporary relief and also potential toxicity.

Thomas, C.L. 1985. Taber's Cyclopedic Medical Dictionary. F.A. Davis Co. Pub., Philadelphia. 2170.


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