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Dihydroxyphenylalanine

Dihydroxyphenylalanine

Dihydroxyphenylalanine (DOPA) is an amino acid produced by the oxidation of tyrosine by the enzyme tyrosinase. It is an intermediate in the catabolism of phenylalanine and tyrosine, and as a precursor to dopamine and norepinephrine, epinephrine, and melanin.

L-dopa, the naturally occurring form, and levodopa, a synthetic form, are used in the treatment of Parkinsonism and manganese poisoning.


References
Stedman, Thomas Lathrop. Stedman's Medical Dictionary. 24th edition. Baltimore: Williams and Wilkins, 1982.

Thomas, C.L. 1985. Taber's Cyclopedic Medical Dictionary. F.A. Davis Co. Pub., Philadelphia. 2170.

 


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