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Kaposi's Syndrome

Kaposi's Syndrome

Also known as Multiple Idiopathic Hemorrhagic Syndrome and Idiopathic Multiple
Pigmented Hemorrhagic Syndrome.

A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal sites. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to skin and subcutaneous tissue, but widespread viseral involvement may occur. Kaposi's sarcoma occurs endemically in certain parts of Central Africa and Central and Eastern Europe, and a particularly virulent and disseminated form occurs in immunocompromised patients (transplant recipients and those with acquired immunodeficiency syndrome - AIDS).

References

Taylor, E.J., Dorland's Illustrated Medical Dictionary 27th Edition, W.B. Saunders, Co. Publishing, Philadelphia, page 177. 1988.

 


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