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Nonspecificly, is any substance depressing the central nervous system and producing stupor associated with analgesia.

Specifically, it is a drug derived from opium or opium-like compounds, with potent analgesic effects associated with significant alterations of mood and behavior, and with the potential for dependence and tolerance following repeated administration.

Moore, M. 1979. Medicinal Plants of the Mountain West. Museum of New Mexico Press, New Mexico.

Thomas, C.L. 1985. Taber's Cyclopedic Medical Dictionary. F.A. Davis Co. Pub., Philadelphia. 2170.