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Clonidine

Drug Name: Clonidine

Drug ID: 135

Nutritional Considerations

  • Maintain a low calorie, low-fat diet with high fiber intake as directed by your physician.

    1. Balch, JF, Balch PA: Prescription for Nutritional Healing, Avery Publishing, 1997
  • Limit alcohol use.

    1. Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 143.
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999
    3. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
  • Clonidine may contribute to the depletion of CoQ10. Supplementation may be beneficial.

    1. Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III - inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pharmacol, 1975, 12(3):533-40.

Herbal Considerations

  • Some herbs possess cardiac properties that may intensify the action of antihypertensive drugs. This could result in an excessive lowering of blood pressure or increased side effects. Such herbs include: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot

    1. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
    2. McGuffin M, et al., ed. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997.
    3. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
    4. PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
  • Avoid natural licorice products, Ginseng, and Ephedra (Ma huang) which may interfere with antihypertensive therapy.

    1. Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227.
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999
    3. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
  • Avoid Yohimbe, which may reverse the effects of Clonidine.

    1. DeSmet PAGM, Smeets OSNM. "Potential risks of health food products containing yohimbe extracts," Br. Med. J., 309:958, 1994.
    2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
    3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

NDC Codes

00054823301, 00228212710, 00228212750, 00228212810, 00228212850, 00228212910, 00339544611, 00339544811, 00339544814, 00364082001, 00364082002, 00378000101, 00378002701, 00378007201, 00378015201, 00378015210, 00378018601, 00378018610, 00378019901, 00440732510, 00440732530, 00440732560, 00440732590, 00440732592, 00440732594, 00440732660, 00440732690, 00440732692, 00440732694, 00615257243, 00615257253, 00615257263, 00615257353, 00615257363, 12634046560, 49884011301, 49884011305, 49884011310, 49884011501, 49884011505, 49884011510, 49884011601, 49884011605, 49884011610, 51079029919, 51079029920, 51079030019, 51079030020, 51079030120, 51129221401, 51129233801, 51655035324, 51655035325, 51655035352, 51655036224, 51655036225, 51655036252, 51655036284, 53002041400, 53002041430, 53002041450, 53002041460, 53002041490, 53978081603, 53978081607, 53978081609, 53978085109, 53978093603, 53978093607, 53978093609, 53978109903, 53978203009, 54569047800, 54569047801, 54569047802, 54569185300, 54569185301, 54569280100, 54868004800, 54868004801, 54868004802, 54868004803, 54868004804, 54868004805, 54868004806, 54868004900, 54868004902, 54868004903, 54868004904, 54868004905, 54868196701, 54868196702