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Deferoxamine

Drug Name: Deferoxamine

Drug ID: 430

Nutritional Considerations

  • nutrient affecting drug performance: Iron Since deferoxamine is administered to individuals with dangerously high levels of iron it would be counter-productive to supplement with iron. An individual on deferoxamine should consult the prescribing physician before using any supplements containing iron.

    1. Hoffbrand AV, Wonke B. Iron chelation therapy. J Intern Med Suppl 1997;740:37-41.
    2. Hoffbrand AV. Prospects for oral iron chelation therapy. J Lab Clin Med 1994 Apr;123(4):492-494.
    3. Hoffbrand AV. Prospects for oral iron chelation therapy. J Lab Clin Med 1994 Apr;123(4):492-494.
    4. Sakagami H, Satoh K, Fukuchi K, Gomi K, Takeda M. Effect on an iron-chelator on ascorbate-induced cytotoxicity. Free Radic Biol Med 1997;23(2):260-270
  • nutrient affecting drug performance: Vitamin C . Vitamin C supplementation, even at low levels (200 mg per day), has consistently enhanced the ability of deferoxamine to rid the body of excess iron even though vitamin C may slightly increase iron absorption. In twelve studies at different dose levels of deferoxamine, ascorbate therapy was associated with increased iron excretion ranging from 24% to 245%.

    1. (Hussain MA, et al. Lancet 1977 May 7;1(8019):977-979.)

NDC Codes