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Lanoxin

Drug Name: Lanoxin

Drug ID: 11

Nutritional Considerations

  • Mineral imbalances can create a dangerous effect on the body when combined with Lanoxin. High calcium levels and low potassium and magnesium levels can create a toxic effect. Low calcium levels can reduce the effectiveness of Lanoxin. Consult with your pharmacist or physician regarding supplementation of minerals.

    1. Drug Interaction Facts, Tatro, D.S., Editor (St Louis, MO, Facts and Comparisons, through July, 1995).
    2. Whang R, Oei TO, Watanabe A. Frequency of hypomagnesiumia in hospitalized patients receiving digitalis. Arch Intern Med 1985;145:655-56.
    3. Holt GA. Food & Drug Interactions. Chicago: Precept Press,1998, 94.
    4. Landauer RA. Magnesium deficiency and digitalis toxicity. JAMA 1984;251:730 [letter/review].
    5. Schwinger RH, Eromann E: Heart failure and electrolyte disturbances, Methods find Exp Clin Pharmacol, 1992, 14(4): 315-25.
    6. Kupfer S, Kosovsky JD: Effects of cardiac glycosides on renal tubular transport of calcium, magnesium, inorganic phosphate and glucose in the dog, J of Clin Investig, 1965, 44:1143.
    7. Pronsky, Z Food Medication Interactions, 11th edition, 1999
  • Digoxin may deplete thiamine with long term use. Discuss supplementation with a pharmacist.

    1. Geriatric Nutrition, 3rd edition (Englewood Cliffs, NJ, Prentice-Hall Inc., 1992).
    2. Zangen A, Botzer D, Zangen R, et al: Furosemide and digoxin inhibit thiamine uptake in cardiac cells, Eur J Pharmacol, 1998, 361 (1):151-5.

Herbal Considerations

  • Avoid natural licorice products, which may cause low levels of potassium.

    1. Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 107.
    2. Tyler VE. The Honest Herbal, 3rd ed. New York: Pharmaceutical Products Press, 1993, 198.
    3. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
  • Avoid using lanoxin with the following herbs: black hellebore, calamus, cereus, cola, coltsfoot, devil's claw, European mistletoe, fenugreek, fumitory, digitalis leaf, hedge mustard, figwort, lily of the valley roots, motherwort, pleurisy root, squill bulb leaf scales, white horehound, mate, scotch broom flower, shepherd's purse, and wild carrot, due to their cardioactive properties.

    1. Brinker, Francis: Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
    2. Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998.
    3. PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
  • Hawthorn can increase the effects of lanoxin. Consult your physician before using both the herb and the medication at the same time.

    1. Brinker, Francis: Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
    2. Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998

NDC Codes

00173024255, 00173024256, 00173024275, 00173024955, 00173024956, 00173024975, 00173024980, 00173026010, 00173026035, 00173026210, 00173026427, 00339519811, 00339519818, 00339520211, 00339520218, 00440768530, 00440768590, 00440768630, 00440768690, 00615051843, 00615051853, 00615051863, 00615054713, 00615054743, 00615054753, 00615054763, 19458018107, 19458054401, 49035012301, 49035019601, 49035019701, 51129131101, 51129174301, 51655001824, 51655001826, 51655001853, 51655037924, 51655037925, 51655037926, 51655037977, 52985000606, 53002036600, 53002036620, 53002036630, 53002036650, 53002036660, 53873026402, 53978017709, 53978020203, 53978020209, 54569048300, 54569048301, 54569048303, 54569048304, 54569048305, 54569048400, 54569048401, 54569048403, 54868068301, 54868068302, 54868068303, 54868068304, 54868079002, 54868079003, 54868079004, 54868079005