Loxitane
Written by YoMax
Drug Name: Loxitane
Nutritional Considerations
Take with food for stomach upset.
- Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
- Pronsky, Z Food Medication Interactions, 11th edition, 1999
Avoid caffeine with this medication.
- Kulhanek F, et al. Precipitation of Antipsychotic drugs in interaction with coffee or tea. Lancet 1979;2:1130.
- Lasswell WL Jr., et al. In vitro interaction of neuroleptics and tricylic antidepressants with coffee, tea, and gallotannic acid. J Pharm Sci 1984; 73:1056-8.
Take magnesium supplements or antacids separated by at least 2 hours from the drug.
- Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
Vitamin E may be helpful in reducing the incidence of tardive dyskinesia associated with the use of this medication.
- Adler LA, et al. Long term treatment effects of vitamin E for tardive dyskinesia. Biol Psychiatry 43: 868-872, 1998
- Inada T: [Recent research trends in diagnosis, treatment, and prevention of drug-induced extrapyramidal symptoms seen in psychiatric patients.] Nihon Shinkei Seishin Yakurigaku Zasshi, 1996 Oct, 16:5, 181-5.
Avoid alcohol with this medication.
- Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
- Pronsky, Z Food Medication Interactions, 11th edition, 1999
Avoid phenylalanine supplements while taking this medication because the risk of tardive dyskinesia may increase.
- Mosnik DM, Spring B, Rogers K, and Baruah SL. Tardive dyskinesia exacerbated after ingestion of phenylalanine by schizophrenic patients. Neuropsychopharmacology 16(2): 136-146, 1997.
- Richardson MA. Amino acids in psychiatric disease. Washington, DC: American Psychiatric Press, 1990.
Herbal Considerations
Avoid tobacco, it may increase metabolism of the drug.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
Evening Primrose Oil may increase seizure potential if used together with this medication.
- PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
Avoid cola nut, cocoa, guarana and mate with this medication due to their caffeine content.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
Kava may increase dystonia if used together with this drug.
- Schelosky L, et al. Kava and dopamine antagonism. J Neurol Neurosurg Psych 58(5): 639-640, 1995
The CNS depressant tendency of: devil's claw, lemonbalm, ma huang, meadowsweet, mullein, peppermint, pokeroot, European poplar, prickly ash, queen of the meadow and sassafras may potentiate CNS side effects of this medication.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
- PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
Avoid alfalfa with this medication due to the increased risk of photosensitivity.
- Brown R. Potential interactions of herbal medicines with antipsychotics, antidepressants and hypnotics. European Journal of Herbal Medicine 1997;3:25-8.
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