Text Size

Site Search powered by Ajax

Loxitane

Drug Name: Loxitane

Drug ID: 343

Nutritional Considerations

  • Take with food for stomach upset.

    1. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999
  • Avoid caffeine with this medication.

    1. Kulhanek F, et al. Precipitation of Antipsychotic drugs in interaction with coffee or tea. Lancet 1979;2:1130.
    2. Lasswell WL Jr., et al. In vitro interaction of neuroleptics and tricylic antidepressants with coffee, tea, and gallotannic acid. J Pharm Sci 1984; 73:1056-8.
  • Take magnesium supplements or antacids separated by at least 2 hours from the drug.

    1. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
  • Vitamin E may be helpful in reducing the incidence of tardive dyskinesia associated with the use of this medication.

    1. Adler LA, et al. Long term treatment effects of vitamin E for tardive dyskinesia. Biol Psychiatry 43: 868-872, 1998
    2. Inada T: [Recent research trends in diagnosis, treatment, and prevention of drug-induced extrapyramidal symptoms seen in psychiatric patients.] Nihon Shinkei Seishin Yakurigaku Zasshi, 1996 Oct, 16:5, 181-5.
  • Avoid alcohol with this medication.

    1. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999
  • Avoid phenylalanine supplements while taking this medication because the risk of tardive dyskinesia may increase.

    1. Mosnik DM, Spring B, Rogers K, and Baruah SL. Tardive dyskinesia exacerbated after ingestion of phenylalanine by schizophrenic patients. Neuropsychopharmacology 16(2): 136-146, 1997.
    2. Richardson MA. Amino acids in psychiatric disease. Washington, DC: American Psychiatric Press, 1990.

Herbal Considerations

  • Avoid tobacco, it may increase metabolism of the drug.

    1. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
  • Evening Primrose Oil may increase seizure potential if used together with this medication.

    1. PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
    2. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
  • Avoid cola nut, cocoa, guarana and mate with this medication due to their caffeine content.

    1. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
  • Kava may increase dystonia if used together with this drug.

    1. Schelosky L, et al. Kava and dopamine antagonism. J Neurol Neurosurg Psych 58(5): 639-640, 1995
  • The CNS depressant tendency of: devil's claw, lemonbalm, ma huang, meadowsweet, mullein, peppermint, pokeroot, European poplar, prickly ash, queen of the meadow and sassafras may potentiate CNS side effects of this medication.

    1. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
    2. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996
    3. PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
  • Avoid alfalfa with this medication due to the increased risk of photosensitivity.

    1. Brown R. Potential interactions of herbal medicines with antipsychotics, antidepressants and hypnotics. European Journal of Herbal Medicine 1997;3:25-8.

NDC Codes

51129213701, 51129220701