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Maxalt

Drug Name: Maxalt

Drug ID: 293

Nutritional Considerations

  • Food decreases absorption rate by one hour but does not interfere with total absorption.

    1. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999.
  • Maxalt may interact with the nutritional supplement 5-HTP, the precursor molecule of serotonin.

    1. Cocks TM: Comparison of contractile responses to 5-hydroxytryptamine and sumatriptan in human isolated coronary artery: synergy with the thromboxane A2-receptor agonist, U46619. Br J Pharmacol, 1993 Sep, 110:1, 360-8.
  • Limit alcohol intake with Maxalt.

    1. Scott AK: Sumatriptan clinical pharmacokinetics. Clin Pharmacokinet, 1994 Nov, 27:5, 337-44.
    2. Pronsky, Z Food Medication Interactions, 11th edition, 1999

Herbal Considerations

  • Prolonged use of the following herbs: Black Hellebore, Buckthorn, Cascara sagrada, Chinese rhubarb, Frangula, Lily-of-the-Valley, Ma-Huang, and Strophanthus can cause arrythmias as a side effect and therefore, may potentiate the adverse reactions of Maxalt.

    1. PDR (Physician's Desk Reference) for Herbal Medicines. Second edition. Medical Economics Company. Montvale, NJ. 2000: 205, 259.
    2. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
    3. Blumenthal, M (Ed.): The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. American Botanical Council. Austin, TX. 1998
  • Avoid using St. John's Wort with this drug. Concomitant use may enhance risk of adverse effects.

    1. Brandes JL, Edvinsson L, Marcus D, et al. New treatment options for migraine. Medscape Neurology Treatment Updates 2000.
    2. Lantz MS, Buchalter E, Giambanco V. St John's Wort and antidepressant drug interactions in the elderly. J Geriatr Psychiatry Neurol. 1999 Spring;12(1):7-10.
    3. Pronsky, Z Food Medication Interactions, 11th edition, 1999

NDC Codes

00006026602, 00006026606, 00006026674, 00006026702, 00006026706, 00006026774, 00006380006, 00006380102, 00006380106