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Pletal

Drug Name: Pletal

Drug ID: 232

Nutritional Considerations

  • A meal high in fat can increase drug absorption, take it 1/2 hour before or two hours after breakfast and dinner.

    1. Pronsky, Z Food Medication Interactions, 11th edition, 1999
  • Avoid grapefruit juice

    1. Pronsky, Z Food Medication Interactions, 11th edition, 1999
    2. Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000

Herbal Considerations

  • Angelica, anise, arnica, asafoetida, bogbean, boldo, danshen, fenugreek, feverfew, garlic, ginger, ginkgo, ginseng (Panax), horse chestnut, licorice, prickly ash, passionflower, poplar, quassia, red clover, and turmeric, may potentiate the effects of this drug due to their antiplatelet effects.

    1. Rosenblatt M, Mindel J. Spontaneous hyphema associated with ingestion of Ginkgo biloba extract. New Engl J Med 1997;336:1108
    2. Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
    3. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
  • Meadowsweet, Poplar and Willow have salicylate properties and this may interact with Pletal.

    1. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
    2. Facts and Comparisons, Review of Natural Products, Clinisphere 2.0, Wolters Kluwer Company, 2000

NDC Codes

46602000205, 46602000405