Ziac
Written by YoMax
Drug Name: Ziac
Nutritional Considerations
The use of alcohol should be limited.
- Mindell, E, Hopkins V: Prescription Alternatives. New Canaan, CT: Keats Publishing, Inc, 1998; p. 143.
- Facts and Comparisons, Clinisphere 2.0, Wolters Kluwer Company, 2000
- Pronsky, Z Food Medication Interactions, 11th edition, 1999
Ziac may contribute to deficiencies in Co-Q-10, magnesium, potassium, zinc, and sodium.
- Shand, D.G.: Clinical pharmacology of the beta-blocking drugs: implications for the postinfarction patient. Circulation, 1983, 67(Supp 1): 12-15.
- Kishi H, Kishi T, Folkers K: Bioenergetics in clinical medicine III--inhibition of coenzyme Q10-enzymes by clinically used antihypertensive drugs, Res Commun Chem Pathol Pharmacol, 1975, 12(3):533-40.
- Martin B, Milligan K. Diuretic-associated hypomagnesiumia in the elderly. Arch Intern Med 1987;147:1768-71.
- Kroenke K, Wood DR, Hanley JF. The value of serum magnesium determination in hypertensive patients receiving diuretics. Arch Intern Med. 1987;147:1553-56.
- Whang R, Whang DD, Ryan MP. Refractory potassium repletion, a consequence of magnesium deficiency. Arch Intern Med 1992;152:40-45.
Herbal Considerations
Natural licorice products, Ginseng , Ginkgo, and Ephedra (Ma huang) may interfere with antihypertensive medications and should be avoided with high blood pressure.
- Pronsky, ZM: Food-Medication Interactions, 11th edition, 1999
- Farese, RV et al., Licorice-induced hypermineralcorticoidism. NEJM. 1991, 325:1,1223-1,227.
- Shaw D et al. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Safety 1997;17:342-56.
- Shintani S, Murase H, Tsukagoshi H, Shiigai T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Report of two cases and review of the literature. Eur Neurol 1992;32:44-51.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
Some herbs possess diuretic properties that may intensify the action of antihypertensive drugs, which could result in an excessive lowering of blood pressure. Such herbs include: Alfalfa, Angelica, Astragalus, Basil, Bean Pod, Buckthorn, Burdock, Butcher’s Broom, Buchu, Celery, Cleavers, Cornflower, Dandelion, Elecampane, Elder, Goat's Rue, Hempnettle, Horsetail, Indian-Hemp, Juniper, Marigold, Meadowsweet, Parsley, Rauwolfia, Sarsaparilla, Sweet clover, Turmeric, and Vervain
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996.
- Brinker, F Herb Contraindications and Drug Interactions, Eclectic Medical Publications, 1998
- Shaw D et al. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Safety 1997;17:342-56.
- PDR for Herbal Medicines, 2nd edition, Medical Economics Company, 2000
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