Abstracts
PMS
PMS
Vitex agnus castus may effectively reduce symptoms of premenstrual syndrome (PMS) when taken daily for at least three menstrual cycles, according to this prospective trial conducted on 43 patients. The participants filled out several questionnaires about their PMS symptoms at 2 months of baseline, after 3 months of treatment with 20 mg Vitex daily, and after three months of post-treatment. Women who supplemented with Vitex reported significant reductions in PMS symptoms after 3 months of treatment. However, the symptoms gradually returned after supplementation ended, but did not reach baseline levels during 3 months post-treatment. During supplementation, about 20 patients experienced adverse effects, including fatigue and headache.
Berger D, Schaffner W, Schrader E, Meier B, Brattstrom A: Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS), Arch Gynecol Obstet 2000 Nov;264(3):150-3