Frangulin Factors
Frangulin factors are a group of two compounds consisting of frangulin A and B. They are found in buckthorn, cascara sagrada and many other plants. Frangulin A and B are anthraquinone glycosides. Like all anthraquinone glycosides, they are cathartic and act on the large intestines to increase peristalsis. Frangulin A and B cause cathartic action through stimulation of the appropriate nerves after being absorbed in the bloodstream.
References
Leung, Albert Y. 1980. Encyclopedia of Common Natural Ingredient used in Food, Drugs and Cosmetics. John Wiley and Sons, N Y. 409 pp.
Weiner, Michael and A. Janet Weiner. 1980. Weiner's Herbal The Guide to Herb Medicine. Stein and Day, N Y. 224 pp.