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Chronic Fatigue Syndrome

Description


Chronic Fatigue Syndrome is an all-encompassing term for symptoms which may actually result from the same or similar source.

There is currently some debate whether there are several names for the same disease, or different stages of one disease, or separate diseases with similar symptoms:

        Autoimmune disorder
        Candida Albicans
        Chronic mononucleosis
        Cytomegalovirus
        Epstein-Barr virus
        Herpes simplex virus
        Myalgic encephalomyelitis (ME)
        Yuppie 'flu


Patients suffering from any of these syndromes may be fatigued and suffer symptoms of a mild infection to a chronic degree.

        

        

Causes

The favorite theory is a viral infection. Which virus, is another matter. There certainly appears to be a continuum of herpes virus, mononucleosis and Epstein-Barr.

However, they need not assert themselves if the host is not compromised, whether with a toxic bowel, or depressed immune system, or both.

Hence, treatments tend to aim at detoxification and immune support.

Signs & Symptoms

        Headache
        Intestinal discomfort
        Low-grade fever
        Lymph node swelling
        Muscle and joint pain
        Recurrent sore throat
        
All of which will impact work performance (hence "Yuppie 'flu")and family life.

Moreover, these symptoms apply to a myriad of other diseases, so a differential diagnosis may be difficult and many sufferers languish for years without proper diagnosis, or treatment. In which case, a referral to a psychiatrist may come none too soon, as they are very likely to be depressed about their quality of life by that time!

Nutritional Supplements

Structure & Function:
        Immune System Support
        Intestinal Health
        Circulatory Support &
        Nutrients for Brain Support


---------------------------------
General Supplements
---------------------------------


Beta-carotene15 mg
Magnesium200-400 mg
Vitamin C 2000- 5000 mg
Zinc15-25 mg




* Please refer to the respective topic for specific nutrient amounts.

Glandular support may also be required, in particular, for the adrenals and thymus.


Note:

All amounts are in addition to those supplements having a Recommended Dietary Allowance (RDA). Due to individual needs, one must always be aware of a possible undetermined effect when taking nutritional supplements. If any disturbances from the use of a particular supplement should occur, stop its use immediately and seek the care of a qualified health care professional.





        

Dietary Considerations

As with other fatigue syndromes, B-complex vitamins may well be indicated, chiefly vitamin B12.

If the CFS condition is accompanied by eczema, essential fatty acid metabolism is suspect and supplementation may be beneficial.

Otherwise, treatment comprises chiefly minerals: germanium and magnesium. Germanium seems to stimulate interferon production which can modulate reactivation of the herpes virus. Magnesium levels are often deficient, so supplementation of magnesium together with vitamin B12 should improve red blood cells.

Another nutritional factor which has been recommended to good efect is coenzyme Q10.

Homeopathic Remedy

DescriptionRemedy
Adrenal insufficiency:Arsenicum Album
Graphites
Sepia
Immune insufficiency:Echinacea angustifolia



Treatment Schedule

Over-the-counter homeopathic remedies may be single strength (of fairly weak potency e.g. 6X ) or a blend of several weaker strengths (6X, 8X, 10X).

This may comprise a single remedy, or several remedies.

Doses are administered on a 3 times daily (tid), between meals,schedule and continued for 3 days.

Liquid preparations usually use 8-10 drops per dose.

Solid preparations are usually 2 or 3 pellets per dose.

Children use 1/2 dose i.e. 1 pellet.

If there is aggravation of the symptoms, stop taking the remedy and consult a homeopath.

References

Murphy, R. : Homeopathic Medical Repertory. Hahneman Academy, Pagosa Springs, Colorado. 1993.

Murphy, R. : Lotus Materia Medica. Hahneman Academy, Pagosa Springs, Colorado. 1995.

Pert, J.C.: Homeopathy for the Family. The Homoeopathic Development Foundation, London. 1985 edition.

Herbal Approaches

----------
Herbs
-----------


Echinacea (Echinacea angustifolia)
Ginseng (Panax ginseng)
Goldenseal (Hydrastis canadensis)
Milk thistle
St. John's wort

Note: The misdirected use of an herb can produce severely adverse effects, especially in combination with prescription drugs. This Herbal information is for educational purposes and is not intended as a replacement for medical advice.

Discussion:

Two herbs are becoming so popular that their wild harvesting has taken them to the brink of extinction:

        Echinacea (Echinacea angustifolia)
        Goldenseal (Hydrastis canadensis)

They seem to benefit the immune system.

The favorite for liver detoxification is Milk thistle (Silybum marianum).

The staple for energy is ginseng (Panax ginseng).

St. John's wort exhibits strong antiviral activity against herpes simplex virus types 1 and 2 as well as Epstein-Barr virus. It also acts as an antidepressant.

References:

Lavie, D: Antiviral pharmaceutical compositions containing hypericin or pseudohypericin. European Patent. 1987.
        
        
        

Aromatherapy - Essential Oils

This is another condition with a typical presentation of multiple symptoms.

Exhaustion:

Basil Essence,Bergamot Essence,
Chamomile Essence,Clary Sage Essence,
Frankincense Essence,Lavender Essence,
Lemon Essence,Neroli Essence,
Orange Essence,Thyme Essence.



Related Health Conditions

        AIDS
        Autoimmune disorders
        Candida Albicans
        Chronic mononucleosis
        Cytomegalovirus
        Epstein-Barr virus
        Herpes simplex virus
        Mononucleosis
        Myalgic encephalomyelitis (ME)
        Shingles (Herpes zoster)
        Yuppie 'flu

Abstracts

References

Behan, P.O. et al: Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol. Scand. 1990, 82(3): 209 - 216.

Buchwald D et al.: Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. Am J Med, 1996 Oct, 101:4, 364-70.

Cater-RE.: Chronic intestinal candidiasis as a possible etiological factor in the chronic fatigue syndrome. Med-Hypotheses. 1995 Jun; 44(6): 507-15.

Chester-AC; Levine-PH: Concurrent sick building syndrome and chronic fatigue syndrome: epidemic neuromyasthenia revisited. Clin-Infect-Dis. 1994 Jan; 18 Suppl 1: S43-8.

Chester AC: Chronic fatigue syndrome criteria in patients with other forms of unexplained chronic fatigue. J Psychiatr Res, 1997 Jan-Feb, 31:1, 45-50.

Cox, I.M. et al: Red blood cell magnesium and chronic fatigue syndrome. Lancet, 1991, 337: 757 - 760.

Derman W et al.: The 'worn-out athlete': a clinical approach to chronic fatigue in athletes. J Sports Sci, 1997 Jun, 15:3, 341-51.

Dickinson CJ: Chronic fatigue syndrome--aetiological aspects [see comments]. Eur J Clin Invest, 1997 Apr, 27:4, 257-67.

Durlach, J.: Chronic fatigue syndrome and chronic primary magnesium deficiency. Magnes. Res. 1992, 5(1): 68.

Faloona, G.R. & Levine, S.A.: The use of organic germanium in chronic Epstein-Barr Virus Syndrome. J. Orthomol. Med. 1988, 3(1): 29 - 31.

Fiedler N et al.: A controlled comparison of multiple chemical sensitivities and chronic fatigue syndrome. Psychosom Med, 1996 Jan-Feb, 58:1, 38-49.

Fischler B et al., Sleep anomalies in the chronic fatigue syndrome. A comorbidity study. Neuropsychobiology, 1997, 35:3, 115-22.

Freeman R & Komaroff AL: Does the chronic fatigue syndrome involve the autonomic nervous system? Am J Med, 102(4):357-64 1997 Apr.

Goldenberg DL: Fibromyalgia, chronic fatigue syndrome, and myofascial pain. Curr Opin Rheumatol, 1996 Mar, 8:2, 113-23.

Grant-JE. et al: Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J-Am-Diet-Assoc. 1996 Apr; 96(4): 383-6

Gray-JB & Martinovic-AM.: Eicosanoids and essential fatty acid modulation in chronic disease and the chronic fatigue syndrome. Med-Hypotheses. 1994 Jul; 43(1): 31-42.

Houde SC et al.: Chronic fatigue syndrome: an update for clinicians in primary care. Nurse Pract, 1997 Jul, 22:7, 30, 35-6, 39-40 passim.

Johnson SK et al., Depression in fatiguing illness: comparing patients with chronic fatigue syndrome, multiple sclerosis and depression. J Affect Disord, 1996 Jun 20, 39:1, 21-30.

Kaslow, J.E. et al: Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch. Int. Med. 1989, 149(11): 2501 - 2503.

Kidd, P.M.: Germanium-132: Homeostatic normalizer and immunostimulant. Int. Clin. Nutr. Rev. 1987, 7(1): 11 - 20.

Kodama M et al., The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). II. Characterization of CFS patients with special reference to their response to a new vitamin C infusion treatment. In Vivo, 1996 Nov-Dec, 10:6, 585-96.

Komaroff AL et al., An examination of the working case definition of chronic fatigue syndrome. Am J Med, 1996 Jan, 100:1, 56-64.

Lapp, C.W.: Chronic fatigue syndrome is a real disease. N. Carolina Family Physician, 1992, 43(1): 6 - 11.

Leese G et al., Short-term night-shift working mimics the pituitary-adrenocortical dysfunction in chronic fatigue syndrome. J Clin Endocrinol Metab, 1996 May, 81:5, 1867-70.

McCully KK et al., Use of exercise for treatment of chronic fatigue syndrome. Sports Med, 1996 Jan, 21:1, 35-48.

Morris-DH & Stare-FJ.: Unproven diet therapies in the treatment of the chronic fatigue syndrome. Arch-Fam-Med. 1993 Feb; 2(2): 181-6.

Plioplys AV & Plioplys S: Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology, 1997, 35:1, 16-23.

Plioplys AV: Antimuscle and anti-CNS circulating antibodies in chronic fatigue syndrome. Neurology, 1997 Jun, 48:6, 1717-9.

Regland B et al., Increased concentrations of homocysteine in the cerebrospinal fluid in patients with fibromyalgia and chronic fatigue syndrome. Scand J Rheumatol, 1997, 26:4, 301-7.

See DM et al., In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunopharmacology, 1997 Jan, 35:3, 229-35.

Sharpe M et al.: Chronic fatigue syndrome. A practical guide to assessment and management. Gen Hosp Psychiatry, 1997 May, 19:3, 185-99.

Shorter-E: Chronic fatigue in historical perspective. Ciba-Found-Symp. 1993; 173: 6-16; discussion 16-22.

Simpson M et al.: Chronic fatigue syndrome/myalgic encephalomyelitis as a twentieth-century disease: analytic challenges. J Anal Psychol, 1997 Apr, 42:2, 191-9.

van Waveren EK et al., The rise and fall of the chronic fatigue syndrome as defined by Holmes. Med Hypotheses, 1996 Feb, 46:2, 63-6.

Wessely S: Chronic fatigue syndrome. Summary of a report of a joint committee of the Royal Colleges of Physicians, Psychiatrists and General Practitioners. J R Coll Physicians Lond, 1996 Nov-Dec, 30:6, 497-504.

Williams G et al., Dissociation of body-temperature and melatonin secretion circadian rhythms in patients with chronic fatigue syndrome. Clin Physiol, 1996 Jul, 16:4, 327-37.

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