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Shark Liver Oil

DESCRIPTION
Shark Liver Oil is obtained from sharks caught for food purposes only, living in cold, deep oceans. The liver oil from sharks has been used by fishermen for centuries as a folk remedy for general debility, for healing wounds, sores, irritations of the respiratory tract and the alimentary canal, and for lymph node swelling. Shark Liver Oil from Greenland is rich in alkylglycerols, which are naturally found in mother's milk and in bone marrow. Shark Liver Oil from Alaska is especially rich in Vitamins A and D and in essential Omega-3 fatty acids.


PHYSIOLOGY
Shark Liver Oil has been studied extensively in Sweden. Alkylglycerols are involved in the production of white blood cells. Shark Liver Oil was found to stimulate the body's immune system, increasing antibodies, leukocytes and thrombocytes. In particular, shark liver oil was found to increase the survival rate of cervical cancer patients and reduce radiation-induced injuries of leukopenia and thrombocytopenia. Recent research has also shown alkyglyerols have antibiotic and anti-fungal effects, can speed up the healing of wounds, and can increase the excretion of mercury.


BIOCHEMISTRY
Greenland Shark Liver Oil contains the highest level of alkylglyerols found in nature. Alkylglycerols are found naturally in bone marrow, liver, spleen, and human breast milk. The active ingredients are predominantly esters of selachyl-, chimyl-, and batyl-alcohol, and methoxy-substituted compounds of glycerol. There are 16 known alkylglycerols. Shark liver oil is also a highly concentrated source of pre-formed Vitamin A -- so much so that large amounts can be toxic.


TOXICITY, CAUTIONS & CONTRA-INDICATIONS
No known toxicity for alkylglycerols, but excessive Vitamin A is toxic. Pre-formed Vitamin A intake should be restricted to 10,000 IU per day for pregnant women, especially in the first trimester, and to 20,000 IU per day in most cases for other adults.


DIRECTIONS FOR USE
50-300 mg alkylglycerols/day; 1-2 capsules 2-3 times daily. Vitamin A should be limited to 20,000 IU per day; women who are or may become pregnant should limit Vitamin A intake to 10,000 IU per day or less.


SAMPLE ANALYSIS

DescriptionClear golden yellow liquid
Odor and tastefishy, but not rancid
Vitamin A 30,000 to 36,000 IU per gram
Free fatty acidNot more than 1.0 %
Moisture & impuritiesNot more than 1.0%
Clear test(Clear at 10x in 8 hrs: passed)
P.C.B. content170 to 187
Iodine value125 to 155
Unsaponifiable matterNot more than 6.0%
Peroxide valueNot more than 10 m'eq/kg
AntioxidantNegative
Heavy MetalsNot more than 10 ppm
Arsenic(Not more than 0.3 ppm)
Mercury(Not more than 0.5 ppm)




ABSTRACTS

Neoplastic disorders

Shark liver oil, which contains alkylglycerol, may be used as a therapeutic and preventive agent for neoplastic disorders and as an immune booster in infectious diseases. Recently, it has been shown that alkylglycerol inhibits the activation of protein kinase C, which contributes to cell proliferation. Other studies indicate that alkylglycerols may stimulate the immune system by acting on macrophages.

Pugliese PT, Jordan K, Cederberg H, Brohult J: Some biological actions of alkylglycerols from shark liver oil, J Altern Complement Med 1998 Spring; 4(1): 87-99



SCIENTIFIC REFERENCES
Brohult, A., et al. (1986) Reduced mortality in cancer patients after administration of alkoxyglycerols. Acta Obstet. Gynecol. Scand. 65:779-785.

Brohult, A. (1962) Alkoxyglycerols in radiation treatment. Nature 193:1304.

Hallgren, B. et al. (1978) Occurance, synthesis, and biological effect of methoxy-substituted glycerol ethers. Progress in Chemistry of Fats and other Lipids. 16:45.

Boeryd, B. et al. (1978) Stimulation of immune reactivity by methoxy-substituted glyerol ether incorporated into the feed. Eur. J. Immunol. 8:678-680.

Hallgren, B. and Larsson,S. (1962) The glycerol ethers in man and cow. J. Lipid Res. 3:31-38.

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