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Abstracts

Infants Development

Infants' development

Taurine may be important to the development of the auditory system among preterm infants. The effects of taurine supplementation among healthy infants less than or equal to 1300 g birth weight were investigated. Growth rate, neurobehavioral development, electroretinographic development, and maturation of auditory brainstem-evoked responses were observed. Infants who received taurine supplementation increased their overall plasma taurine concentrations and had more mature auditory-evoked responses at 37 weeks' postmenstrual age. Further study is needed to confirm the benefits of taurine supplementation on the development of preterm infants.

Vaughan, L.A.; Manore, M.M: Randomized trial of taurine supplementation for infants less than or equal to 1,300-gram birth weight: effect on auditory brainstem-evoked responses, American Academy of Pediatrics. Mar 1989. v. 83 (3) 406-415

Alcohol & Taurine

Alcohol

Taurine may influence the aversive or rewarding effects of ethanol. In a study, rats were administered taurine supplements to examine their response to ethanol. Among the placebo group, they had a significant aversion for the vinegar stimulus. The taurine group had significantly lowered ethanol aversion to ethanol. Taurine may affect an individual's response to ethanol.

Quertemont, E; Goffaux, V; Vlaminck, AM; Wolf, C; De Witte, P: Oral taurine supplementation modulates ethanol-conditioned stimulus preference, Alcohol. 1998 Oct; 16(3): 201-6

Diabetes & Taurine

Diabetes

According to in vitro experiments, taurine may reduce platelet aggregation among diabetic patients. Before taurine supplementation, plasma and platelet taurine concentrations (65.5mmol) were reduced among diabetic patients compared to the control group (93.3mmol). After supplementation, both plasma and platelet taurine concentrations among the diabetic patients reached the standard values among the control group. Taurine may be beneficial for diabetic patients.

Franconi, F; Bennardini, F; Mattana, A; Miceli, M; Ciuti, M; Mian, M; Gironi, A; Anichini, R; Seghieri, G: Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation, Am-J-Clin-Nutr. 1995 May; 61(5): 1115-9

Taurine Deficiency

Taurine deficiency

Taurine supplementation may be required among children who are receiving long-term total parenteral nutrition (TPN). In a trial, children receiving TPN solution without taurine had a fasting plasma taurine level of 26 mumol compared to the level of the control group (57mumol). Later, four children who received TPN with taurine had their plasma taurine level returned to normal. Children on long-term total parenteral nutrition may require taurine supplementation.

Ament, ME; Geggel, HS; Heckenlively, JR; Martin, DA; Kopple, J: Taurine supplementation in infants receiving long-term total parenteral nutrition, J-Am-Coll-Nutr. 1986; 5(2): 127-35

Trauma

Trauma

The effects of taurine supplementation on serum taurine levels among trauma patients were examined. In this study, trauma patients were randomly given one of three dosages of intravenous taurine supplementation. Serum taurine concentrations significantly increased within a week compared to control values. However, patients receiving the highest dosage only regained about one-half of the normal taurine concentrations. Taurine supplementation may not fully correct hypotaurinemia in trauma patients.

Paauw, JD; Davis, AT: Taurine supplementation at three different dosages and its effect on trauma patients, Journal: Am-J-Clin-Nutr. 1994 Aug; 60(2): 203-6

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