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Abstracts

Parkinson's Disease & Tryptophan

Parkinson's Disease

L-tryptophan supplementation during levodopa therapy may prevent motor complications.
In a clinical trial, two patients with Parkinson's disease took L-tryptophan in addtion to levodopa, a Parkinson's disease drug. The women experienced dramatic improvement in their levodopa-induced "On-Off" condition after L-tryptophan supplementation. L-trpytophan may be used during levodopa therapy in preventing levodopa-induced motor complications.

Sandyk, R; Fisher, H: L-tryptophan supplementation in Parkinson's disease, Int-J-Neurosci. 1989 Apr; 45(3-4):
215-9

Exercise Performance & Tryptophan

Exercise Performance

L-tryptophan may increase endurance and pain tolerance during strenuous exercise. According to this study, twelve men performed a workload up to 80% of their maximal oxygen uptake after receiving a placebo and L-tryptophan at two different intervals. L-tryptophan increase total exercise time by 49.4% compared to the placebo. A lower rate of perceived exertion by the tryptophan supplement group was observed although actual exertion by both placebo and experimental groups were similar.

Segura, R; Ventura, JL: Effect of L-tryptophan supplementation on exercise performance, Int-J-Sports-Med. 1988 Oct; 9(5): 301-5


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