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Antacids

Generic and Trade Names:

Aluminum hydroxide (Amphojel)
Aluminum hydroxide and Magnesium trisilicate (Gaviscon)
Calcium carbonate (Tums)
Dihydroxyaluminum sodium carbonate(Rolaids)
Magnesium hydrox/ Aluminum hydrox/ and simethicone (Mylanta)
Magnesium hydroxide and Aluminum hydroxide (Maalox)



Description:

There are several different products available to reduce stomach acid secretion.
The products formulated with calcium carbonate to neutralize stomach acids, are now also being used as an inexpensive source of calcium for the body, to fight against osteoporosis.

Other formulations may feature aluminum (Amphogel), or aluminum plus magnesium (Mylanta) or sodium bicarbonate (Alka Seltzer).

Most formulations can impair nutrient absorption and inhibit gastric acid secretion. (Facts and Comparisons 1999)

Nutritional Considerations:

Take separately from foods high in: fiber, or acidic foods containing oxalates (chiefly fruits and vegetables) or phytates (e.g. nuts, grains and kidney beans). (Pronsky 1999)

Magnesium containing antacids may cause diarrhea and aluminum and calcium containing products may cause constipation. (Facts and Comparisons 1999)

Limit alcohol. (Pronsky 1999)

Limit coffee. (Pronsky 1999)

Aluminum and Magnesium containing antacids can deplete Calcium with long term use. (Spencer 1979)

Copper, Iron, Phosphate and zinc may also be depleted with long term use of some antacids. (Pronsky 1999)

In the case of sodium bicarbonate preparations, there is potassium depletion. (Rhodes 1982)

Herbal Considerations:

Angelica, cinnamon, capsicum, dandelion, devil's claw, gentian, guarana, mate and wormwood might increase stomach acid production and could therefore counteract the effect of antacids. (Brinker 1998)

Rose hips should not be taken with aluminum containing antacids because it can increase aluminum absorption. (Hansten 1997)

Due to presence of salicylates in meadowsweet, plasma salicylate concentration may be decreased if antacids are used at the same time. (Newall 1996)

Other herbs, containing irritants, may theoretically exacerbate the symptoms for which antacids are being taken. (Newall 1996)

Alfalfa
Arnica        
Asafetida
Blue Flag
Boldo
Buchu
Capsicum                                
Cassia
Cinnamon oil
Blue Cohosh,
Eucalyptus        
Figwort
Raw Garlic clove
Ground Ivy         
Guaiacum
Horse chestnut        
Hydrangea
Juniper        
Lemon Verbena
Lime Flowe
Nettle
Parlsey
Pennyroyal
Pleurisy Root
Pokeroot        
Pulsatilla
Queen's Delight
Sarsaparilla
Skunk Cabbage
Squill

References

Basu, T.K. : Drug-Nutrient Interactions. Helm, London. 1988.

Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Facts and Comparisons. Clinisphere 2.0, Wolters Kluwer Company, 1999.

Hansten PD, Horn JR. Drug Interactions Analysis and Management. Applied Therapeutics Inc., 1997 and updates.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-care Professionals. London: The Pharmaceutical Press, 1996

Pronsky, Zaneta. Food Medication Interactions. 11th edition. 1999.

Spencer H, Lender M. Adverse effects of aluminum-containing antacids on mineral metabolism. Gastroenterology. 1979 Mar;76(3):603-6.



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