Antacids
Aluminum hydroxide (Amphojel, Di-Gel)
Aluminum hydroxide and Magnesium trisilicate (Gaviscon)
Calcium carbonate (Tums)
Dihydroxyaluminum sodium carbonate (Rolaids)
Magnesium hydrox, Aluminum hydrox, and simethicone (Mylanta)
Magnesium hydroxide and Aluminum hydroxide (Maalox)
Sodium bicarbonate (Alka Seltzer)
Nutritional Considerations:
Take separately from foods high in fiber or acidic foods. (Pronsky 1999)
Be aware that magnesium-containing antacids (Gaviscon, Maalox, and Mylanta) may cause diarrhea and aluminum- and calcium- containing products (Amphojel, Di-Gel, Gaviscon, Maalox, Mylanta, Rolaids, and Tums) may cause constipation. (Facts and Comparisons 2000)
Limit alcohol. (Pronsky 1999)
Limit caffeine. (Pronsky 1999)
Long term use of antacids increases risk of urinary loss of riboflavin. Discuss supplementation with a pharmacist. (Feldman 1983)
Aluminum containing antacids (Amphojel, Di-Gel, Gaviscon, Maalox, Mylanta) can lower calcium levels with long-term use. (Spencer 1983)
Long-term use of antacids can cause malabsorption of phosphate. Calcium, vitamin D, and phosphate supplementation may be required to prevent bone damage. Antacids should not be used long term without consulting a physician. Ask your pharmacist regarding possible supplementation. (Woodson 1998)
Herbal Considerations:
Angelica, cinnamon, capsicum, dandelion, devil's claw, gentian, guarana, mate and wormwood might increase stomach acid production and could therefore counteract the effect of antacids. Consult your pharmacist before taking these herbs with antacids. (Brinker 1998)
Rose hips should not be taken with aluminum-containing antacids (Amphojel, Di-Gel, Gaviscon, Maalox, Mylanta) because it can increase aluminum absorption. (Hansten 1997)
References:
Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Facts and Comparisons. Clinisphere 2.0, Wolters Kluwer Company, 2000.
Feldman S, Hedrick W. Antacid effects of the gastrointestinal absorption of riboflavin. J Pharm Sci 1983 Feb; 72(2): 121-3
Hansten PD, Horn JR. Drug Interactions Analysis and Management. Applied Therapeutics Inc., 1997 and updates.
Pronsky, Zaneta. Food Medication Interactions. 11th edition. 1999.
Spencer H and Kramer L Antacid-induced calcium loss. Arch intern Med 143: 657-658, 1983.
Woodson GC. An interesting case of osteomalacia due to antacid use associated with stainable bone aluminum in a patient with normal renal function. Bone 1998 Jun; 22(6): 695-8.
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